Table 2.
Characteristics | Dementia HR (95% CI) |
Loss of Independence HR (95% CI) |
ADL Disability HR (95% CI) |
IADL Disability HR (95% CI) |
Mobility Disability HR (95% CI) |
---|---|---|---|---|---|
Model 1 (Unadjusted)* | |||||
Frailty | 2.74 (2.02,3.73) | 2.53 (1.81,3.55) | 2.41 (1.69,3.43) | 1.78 (1.23,2.59) | 2.97 (2.11,4.18) |
Model 2† | |||||
Frailty | 2.03 (1.46,2.83) | 1.94 (1.35,2.78) | 1.90 (1.28,2.82) | 1.38 (0.93,2.04) | 2.40 (1.62,3.57) |
Model 3‡ | |||||
Frailty | 2.07 (1.48,2.88) | 1.88 (1.30,2.70) | 1.81 (1.22,2.67) | 1.33 (0.89,1.98) | 2.28 (1.54,3.38) |
Model 4§ | |||||
Frailty | 2.02 (1.43,2.84) | 1.84 (1.28,2.65) | 1.82 (1.24,2.67) | 1.31 (0.89,1.94) | 2.17 (1.48,3.19) |
ADL = activities of daily living; BMI = body mass index; CI = confidence interval; HR = hazard ratio; IADL = instrumental activities of daily living.
Frailty was assessed by the physical frailty phenotype paradigm that is grounded in 5 criteria: exhaustion, low physical activity, weakness, slowness, and unintentional weight loss (www.nhats.org).
Model 2 was adjusted for age, gender, race/ethnicity, census division, residence, and income.
Model 3 was adjusted for age, gender, race/ethnicity, census division, residence, income, BMI, and smoking status.
Model 4 was adjusted for age, gender, race/ethnicity, census division, residence, income, BMI, smoking status, diabetes, hypertension, and number of chronic diseases.