Table 3.
rs ID | Location | Allele | Consequence | Gene symbol | FDR (Spearman) | Captured alleles (Tagger) |
---|---|---|---|---|---|---|
A | ||||||
rs3027012 | 1:159204333-159204333 | T | 5' UTR | ACKR1 | 0.000119 | rs3027008, rs6676002 |
rs72717040 | 1:161517662-161517662 | C | Intronic | FCGR2A | 0.004313 | rs17400517 |
rs7683365 | 4:143999443-143999443 | A | Missense | GYPB | 0.000161 | rs7662277, rs7666297, rs7666296, rs12499907, rs12499906, rs10002395, rs10025455, rs7661933 |
rs17622656 | 5:132485305-132485305 | A | Intronic | IRF1 | 0.002085 | |
rs2770146 | 9:117711060-117711060 | C | Intronic | TLR4 | 0.000303 | rs5030728 |
rs2285002 | 14:64816958-64816958 | A | Intronic | SPTB | 0.005651 | |
rs12587471 | 14:64825597-64825597 | G | Intronic | SPTB | 0.004638 | rs11158561, rs4899147 |
rs7149121 | 14:64864227-64864227 | C | Intronic | SPTB | 0.000360 | |
rs28370916 | 14:64879376-64879376 | G | Intronic | SPTB | 0.008414 | |
rs8081235 | 17:15964787-15964787 | T | Intronic | ADORA2B | 0.001541 | |
rs8081547 | 17:15965007-15965007 | T | Intronic | ADORA2B | 0.000487 | |
B | ||||||
rs6840234 | 4:143996657-143996657 | C | intronic | GYPB | 0.000468 | rs6857129, rs4835127, rs1473055, rs6537238, rs4835126, rs6816184 |
rs8176725 | 9:133257230-133257230 | A | intronic | ABO | 0.009139 | |
rs74056021 | 14:64802733-64802733 | C | intronic | SPTB | 0.001538 | rs74056022, rs45617438 |
rs1535450 | 14:64840590-64840590 | T | intronic | SPTB | 0.003294 | rs1475101 |
rs28998799 | 17:27799104-27799105 | - | intronic | NOS2 | 0.000173 | |
rs4646120 | X:15599613-15599613 | A | intronic | ACE2 | 0.006377 | |
rs1978124 | X:15599940-15599940 | C | intronic | ACE2 | 0.001095 |
The first column “rsID” indicates the tag SNVs. “Location” column indicates chromosome and position in the Human Reference Genome Hg38; “Allele” column is the variant allele, “Consequence” column represents the impact of the variant (rsID) on the protein, and the “Gene symbol” is the gene where the variant is located. In “FDR (Spearman)” the FDR value for each SNVs has been reported (data from the first wave). The last column “Captured alleles (Tagger)” displays the rs number of all the SNVs in linkage disequilibrium with the tag SNV, according to Tagger analysis.