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. 2021 Apr 26;12:655816. doi: 10.3389/fpsyt.2021.655816

Figure 4.

Figure 4

Interaction of candidate genes and proteins. (A) Ethanol significantly increased the ERR and twins transcript levels and significantly reduced the CG10672/dPECR transcript level in the fly heads. (B) In ethanol-naïve hangAE10 mutant flies, the CG10672/dPECR, Ku80, and Gpdh1 transcript levels were significantly reduced. (C) In ethanol-naïve ERR, twins, and Gpdh1 mutants, the hang transcripts were significantly reduced. N = 4 different RNA samples; the data are presented as the means ± STDEV. Significance was determined using a two-tailed t test. *P < 0.05, **P < 0.01, and ***P < 0.001. (D) The interconnection analysis at the protein level was generated by a data bank analysis and was supported by experimental data as described in Supplementary Table 4.