Table 7. Effects of global spinopelvic parameters on disc composition measured by linear regression with mixed effects controlled by age.
| Nucleus pulposus (NP) | Posterior annulus fibrosus (PAF) | Anterior annulus fibrosus (AAF) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Effect (β) | P | 95% CI | Effect (β) | P | 95% CI | Effect (β) | P | 95% CI | ||||||
| SVA | ||||||||||||||
| L1L2 | −0.13 | 0.30 | −0.37 | 0.12 | 0.06 | 0.73 | −0.27 | 0.39 | −0.05 | 0.83 | −0.48 | 0.39 | ||
| L2L3 | −0.13 | 0.29 | −0.37 | 0.11 | −0.04 | 0.83 | −0.36 | 0.29 | 0.20 | 0.36 | −0.23 | 0.64 | ||
| L3L4 | 0.10 | 0.43 | −0.15 | 0.34 | 0.00 | 0.99 | −0.33 | 0.33 | 0.37 | 0.09 | −0.06 | 0.81 | ||
| L4L5 | −0.14 | 0.28 | −0.38 | 0.11 | −0.03 | 0.88 | −0.35 | 0.30 | −0.09 | 0.68 | −0.53 | 0.35 | ||
| L5S1 | −0.33 | <0.01* | −0.58 | −0.09 | 0.17 | 0.30 | −0.16 | 0.50 | −0.07 | 0.74 | −0.51 | 0.36 | ||
| Mean | −0.13 | 0.14 | −0.29 | 0.04 | 0.03 | 0.79 | −0.21 | 0.28 | 0.07 | 0.66 | −0.25 | 0.40 | ||
| CPA | ||||||||||||||
| L1L2 | −0.33 | 0.34 | −0.99 | 0.34 | −0.66 | 0.17 | −1.60 | 0.27 | 0.45 | 0.48 | −0.79 | 1.70 | ||
| L2L3 | 0.42 | 0.22 | −0.25 | 1.09 | −0.40 | 0.40 | −1.34 | 0.54 | 0.17 | 0.78 | −1.07 | 1.42 | ||
| L3L4 | 1.01 | <0.01* | 0.34 | 1.68 | −0.12 | 0.80 | −1.06 | 0.82 | 0.22 | 0.73 | −1.02 | 1.46 | ||
| L4L5 | 0.13 | 0.71 | −0.54 | 0.79 | −0.13 | 0.79 | −1.07 | 0.81 | −0.19 | 0.76 | −1.44 | 1.05 | ||
| L5S1 | −0.57 | 0.09 | −1.24 | 0.10 | 0.39 | 0.41 | −0.55 | 1.33 | −1.92 | 0.00 | −3.16 | −0.67 | ||
| Mean | 0.13 | 0.65 | −0.44 | 0.70 | −0.18 | 0.66 | −1.02 | 0.65 | −0.25 | 0.65 | −1.36 | 0.86 | ||
| L1-S1 | ||||||||||||||
| L1L2 | 1.63 | 0.05 | 0.01 | 3.26 | −0.27 | 0.83 | −2.70 | 2.17 | 2.08 | 0.21 | −1.15 | 5.32 | ||
| L2L3 | 2.25 | <0.01* | 0.62 | 3.87 | −0.03 | 0.98 | −2.46 | 2.41 | 1.73 | 0.29 | −1.51 | 4.96 | ||
| L3L4 | 2.60 | <0.01* | 0.98 | 4.23 | 0.21 | 0.86 | −2.22 | 2.65 | 1.78 | 0.28 | −1.46 | 5.01 | ||
| L4L5 | 2.05 | 0.01* | 0.42 | 3.67 | 0.22 | 0.86 | −2.22 | 2.65 | 1.54 | 0.35 | −1.69 | 4.78 | ||
| L5S1 | 1.68 | 0.04* | 0.05 | 3.30 | 0.60 | 0.63 | −1.83 | 3.04 | 0.56 | 0.73 | −2.67 | 3.79 | ||
| Mean | 2.04 | 0.01* | 0.43 | 3.65 | 0.15 | 0.91 | −2.28 | 2.57 | 1.54 | 0.35 | −1.68 | 4.76 | ||
| T1-S1 | ||||||||||||||
| L1L2 | 0.12 | 0.82 | −0.95 | 1.20 | −0.73 | 0.36 | −2.29 | 0.83 | 0.47 | 0.66 | −1.62 | 2.55 | ||
| L2L3 | 0.37 | 0.50 | −0.71 | 1.44 | −0.64 | 0.42 | −2.20 | 0.92 | 0.34 | 0.75 | −1.74 | 2.43 | ||
| L3L4 | 0.50 | 0.36 | −0.57 | 1.57 | −0.56 | 0.48 | −2.12 | 1.00 | 0.36 | 0.73 | −1.72 | 2.45 | ||
| L4L5 | 0.27 | 0.62 | −0.80 | 1.35 | −0.55 | 0.49 | −2.10 | 1.01 | 0.26 | 0.80 | −1.82 | 2.35 | ||
| L5S1 | 0.13 | 0.81 | −0.94 | 1.21 | −0.40 | 0.61 | −1.96 | 1.16 | −0.11 | 0.92 | −2.19 | 1.97 | ||
| Mean | 0.28 | 0.61 | −0.79 | 1.35 | −0.58 | 0.47 | −2.13 | 0.98 | 0.27 | 0.80 | −1.82 | 2.35 | ||
| SSA | ||||||||||||||
| L1L2 | 0.21 | 0.34 | −0.23 | 0.65 | 0.61 | 0.06 | −0.01 | 1.24 | 0.97 | 0.02* | 0.13 | 1.81 | ||
| L2L3 | 0.31 | 0.16 | −0.13 | 0.75 | 0.65 | 0.04* | 0.02 | 1.28 | 0.92 | 0.03* | 0.08 | 1.76 | ||
| L3L4 | 0.37 | 0.10 | −0.07 | 0.81 | 0.68 | 0.03* | 0.06 | 1.31 | 0.92 | 0.03* | 0.08 | 1.76 | ||
| L4L5 | 0.28 | 0.21 | −0.16 | 0.72 | 0.69 | 0.03* | 0.06 | 1.32 | 0.88 | 0.04* | 0.04 | 1.72 | ||
| L5S1 | 0.22 | 0.32 | −0.22 | 0.66 | 0.75 | 0.02* | 0.12 | 1.38 | 0.72 | 0.09 | −0.12 | 1.56 | ||
| Mean | 0.28 | 0.21 | −0.16 | 0.72 | 0.68 | 0.03* | 0.05 | 1.31 | 0.88 | 0.04* | 0.04 | 1.72 | ||
SVA, sagittal vertical axis; CPA, C2 pelvic angle; L1-S1, L1 to S1 length; T1-S1, T1 to S1 length; SSA, spinosacral angle. *P<0.05.