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. 2021 Apr 26;12:662362. doi: 10.3389/fimmu.2021.662362

Figure 5.

Figure 5

Ebosin inhibited the inflammatory response and IL-17 signaling pathway. (A) RT-PCR analyses of cytokines in psoriasis-like mice without or with Methotrexate (MTX) and Ebosin. (B) RT-PCR analyses of tnfaip3 and tnip1 in psoriasis-like mice without or with MTX and Ebosin. (C) Western blotting analyses for proteins on IL-17 signaling pathway in psoriasis-like mice without or with MTX and Ebosin, including A20, Act1, TRAF6, and phosphor-p65. All data were presented as mean ± SD; n = 3. # P < 0.05, ## P < 0.01, ### P < 0.001 vs. control; * P < 0.05, **P < 0.01, ***P < 0.001 vs. IMQ-induced vehicle group.