Table 3.
Anticoagulation day prior to ROTEM blood withdrawal in COVID-19 patients per week from intubation.
| Week number | 1 | 2 | 3* | 4 | 5 | 6 | |
|---|---|---|---|---|---|---|---|
| ANTICOAGULATION | |||||||
| Number of patients | 12 | 15 | 22 | 19 | 17 | 11 | |
| UNFRACTIONATED HEPARIN (UFH) | |||||||
| UFH use | 2 (16.7) | 4 (26.7) | 9 (40.9) | 4 (21.1) | 2 (11.8) | 0 (0) | |
| UFH dosage (×1,000 IU) | 45.2 [–, –] | 43.4 [34.5–59.3] | 41.1 [31.2–48.0] | 41.9 [35.5–44.4] | 39.6 [–, –] | – | |
| Anti-Xa (IU/ml) | 0.75 (–) | 0.61 (0.38) | 0.91 (0.51) | 0.77 (0.30) | 0.53 (–) | – | |
| Missing data | 1 | 1 | 1 | 1 | 0 | – | |
| LOW-MOLECULAR-WEIGHT HEPARIN (LMWH) | |||||||
| LMWH use | Total | 10 (83.3) | 11 (73.3) | 13 (59.1) | 14 (73.3) | 15 (88.2) | 10 (90.9) |
| Prophylactic | 6 (60.0) | 5 (45.5) | 6 (46.2) | 4 (28.6) | 4 (26.7) | 3 (30) | |
| Therapeutic | 4 (40.0) | 6 (54.5) | 7 (53.8) | 10 (71.4) | 11 (73.3) | 7 (70) | |
| Anti-Xa (IU/ml) | 0.52 (0.21) | 0.49 (0.29) | 0.46 (0.23) | 0.53 (0.23) | 0.57 (0.22) | 0.64 (0.25) | |
| Missing data | 0 | 1 | 1 | 2 | 1 | 4 | |
| OTHERS | |||||||
| Fondaparinux use | – | – | – | – | – | 1 (9.1) | |
| No anticoagulation | – | – | 1 (4.5) | 1 (5.3) | – | – | |
Results are presented as n (%) for categorical data and mean (standard deviation) or median [25th percentile−75th percentile] for continuous data. Blood withdrawal for ROTEM measurements was performed from 4:30 to 5:30 a.m.; thus, anticoagulation the day prior to blood withdrawal is presented.
*
One patient received both UFH and LMWH the day prior to blood withdrawal.