Table 2.

DHODH inhibitors currently evaluated in clinical trials

Drug	Clinical trial	Disease	Clinical trial identifier	Study start date
Brequinar	Phase I/II	Acute myeloid leukemia	NCT03760666	November 26, 2018
Leflunomide	Phase I/II	Multiple myeloma	NCT02509052	November 2, 2015
Teriflunomide	Phase IV	Multiple sclerosis	NCT01970410	October 2013
ASLAN003	Phase II	Acute myeloid leukemia	NCT03451084	January 5, 2018
BAY2402234	Phase I	Leukemia	NCT03404726	March 29, 2018
IMU-838	Phase II	Ulcerative colitis	NCT03341962	March 15, 2018
PTC299	Phase I	Acute myeloid leukemia	NCT03761069	October 29,2018