Table 2. Studies published since 1999 on survival and prognostic factors after pulmonary metastasectomy for pulmonary metastasis from head and neck cancers.
| First author | Publication year | Study period | N | 5-year survival | Factors predicting a worse prognosis |
|---|---|---|---|---|---|
| Liu (14) | 1999 | 1966–1995 | 83 | 50.0% | Age >50 years, DFI ≤24 months, incomplete resection |
| Winter (10) | 2008 | 1984–2006 | 67 | 20.9% | Incomplete resection, postoperative complications, adjuvant therapy for primary tumor |
| Chen (15) | 2008 | 1991–2007 | 20 | 59.4% | Male, Sq, DFI <1 year |
| Haroa (16) | 2010 | 1981–2008 | 25 | 50.0% | Age ≥60 years, Sq (oral cavity, pharynx) |
| Shiono (17) | 2009 | 1980–2006 | 114 | 26.5% | Male, Sq, oral cavity cancer, lymph node metastasis, incomplete resection |
| Daiko (18) | 2010 | 1992–2006 | 33 | 43.0% (3-year survival) | DFI ≤2 years, Sq, tongue primary |
| Miyazaki (19) | 2013 | 1999–2009 | 24 | 68.0% (3-year survival) | DFI ≤21.4 months, recurrence before surgery |
| Yotsukura (20) | 2015 | 1986–2013 | 34 | 57.9% | Age, Sq, DFI ≤26 months |
| Oki (21) | 2019 | 1992–2013 | 77 | 54.0% | DFI <18 months, Sq, recurrence before surgery, tumor size >2.5 cm |
a, this study included thyroid cancer as a primary site. Sq, squamous cell carcinoma; DFI, disease-free interval; NA, not available.