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. 2021 Apr;13(4):2447–2459. doi: 10.21037/jtd-21-212

Figure 2.

Figure 2

CircRNA 010567-siRNA protected H9c2 cells against hypoxia-induced cell damage. CircRNA 010567-siRNA, control-siRNA, miR-141 inhibitor, or inhibitor control were transfected into H9c2 cells under hypoxic conditions. (A) qRT-PCR analysis of circRNA 010567 levels in H9c2 cells after circRNA 010567-siRNA treatment. (B) The expression of miR-141 in miR-141 inhibitor-transfected cells. (C) MiR-141 expression in H9c2 cells after circ-siRNA and miR-141 inhibitor treatment. The release of CK-MB (D), cTnI (E), and mitochondrial viability (F) in different groups. Results were shown as mean ± SD. **, P<0.01 vs. control-siRNA; ##, P<0.01 vs. inhibitor control; &&, P<0.01 vs. circRNA-siRNA + inhibitor control; aa, P<0.01 vs. control; bb, P<0.01 vs. hypoxia + control-siRNA; cc, P<0.01 vs. hypoxia + circ-siRNA + inhibitor control.