Figure 3.

Representative pictures of cell nuclei from primary colorectal cancer, endoluminal implant and normal mucosa after hybridization with two probes for chromosome 7 (7p11.1 and 7q31; green and red signals, respectively), three probes for chromosome 8 (8p22, 8p11, and 8q24; red, aqua and green signals, respectively), one probe for chromosome 13q (13q14; red signals) and two probes (break apart probes) for chromosome 18q (18q21; green and red signals). All cell nuclei of both tumors showed a normal diploid number of hybridization signals for the probes of the chromosome 7 and 13q and loss of a whole chromosome 8 and of the 18q21 chromosomal region, suggesting a common clonal origin.