Prognostic significance of the SII in HCC patients with normal AFP levels (AFP <20 ng/mL). Kaplan-Meier analysis of RFS and OS based on the SII in the training (A) and validation (B) cohorts. SII, systemic immune-inflammation index; HCC, hepatocellular carcinoma; AFP, alpha-fetoprotein; OS, overall survival; RFS, recurrence-free survival.