Table 3. The time-dependent AUC of inflammatory indexes in the training and validation cohorts.
| Variable | 12 months | 24 months | 36 months | 60 months | C-index |
|---|---|---|---|---|---|
| Training cohort | |||||
| SII | 0.677 (0.617–0.734) | 0.683 (0.622–0.742) | 0.742 (0.680–0.804) | 0.777 (0.695–0.858) | 0.694 (0.633–0.754) |
| PLR | 0.633 (0.569–0.697) | 0.6021 (0.537–0.668) | 0.605 (0.535–0.674) | 0.608 (0.515–0.700) | 0.607 (0.542–0.672) |
| NLR | 0.638 (0.569–0.707) | 0.600 (0.532–0.668) | 0.613 (0.541–0.684) | 0.677 (0.589–0.766) | 0.624 (0.558–0.691) |
| MELD | 0.596 (0.519–0.673) | 0.583 (0.513–0.652) | 0.569 (0.496–0.643) | 0.497 (0.404–0.590) | 0.584 (0.514–0.653) |
| CTP | 0.496 (0.472–0.520) | 0.497 (0.483–0.512) | 0.501 (0.487–0.516) | 0.496 (0.489–0.504) | 0.498 (0.484–0.512) |
| Validation cohort | |||||
| SII | 0.712 (0.641–0.782) | 0.763 (0.696–0.829) | 0.752 (0.676–0.829) | 0.713 (0.590–0.836) | 0.758 (0.687–0.828) |
| PLR | 0.610 (0.536–0.683) | 0.608 (0.535–0.682) | 0.602 (0.525–0.680) | 0.634 (0.509–0.7600) | 0.628 (0.557–0.700) |
| NLR | 0.549 (0.453–0.644) | 0.527 (0.436–0.617) | 0.572 (0.481–0.663) | 0.700 (0.565–0.774) | 0.565 (0.477–0.653) |
| MELD | 0.456 (0.361–0.550) | 0.452 (0.363–0.541) | 0.465 (0.374–0.556) | 0.406 (0.279–0.533) | 0.452 (0.364–0.540) |
| CTP | 0.486 (0.458–0.512) | 0.489 (0.469–0.510) | 0.492 (0.477–0.508) | 0.494 (0.482–0.506) | 0.491 (0.473–0.509) |
NLR, neutrophil lymphocyte ratio; SII, systemic immune inflammatory index; PLR, platelet lymphocyte ratio; CTP, Child-Turcotte-Pugh; MELD, Model for End-Stage Liver Disease.