Table 7. The C-indexes of the established nomograms and other conventional staging systems.
C‐index | OS | RFS | |||
---|---|---|---|---|---|
Training cohort | Validation cohort | Training cohort | Validation cohort | ||
Nomogram | 0.761 (0.734–0.788) | 0.715 (0.676–0.754) | 0.736 (0.710–0.762) | 0.683 (0.643–0.723) | |
AJCC | 0.710 (0.681–0.739)* | 0.686 (0.646–0.726)* | 0.700 (0.674–0.726)* | 0.643 (0.602–0.684)* | |
BCLC | 0.674 (0.647–0.701)* | 0.643 (0.600–0.686)* | 0.665 (0.640–0.690)* | 0.609 (0.566–0.652)* | |
JIS | 0.690 (0.660–0.720)* | 0.684 (0.643–0.725)* | 0.679 (0.654–0.704)* | 0.649 (0.608–0.690)* | |
CNLC | 0.693 (0.664–0.722)* | 0.655 (0.610–0.700)* | 0.673 (0.645–0.701)* | 0.622 (0.582–0.662)* | |
CLIP | 0.635 (0.606–0.664)* | 0.655 (0.614–0.696)* | 0.636 (0.608–0.664)* | 0.641 (0.600–0.682)* | |
SOLMR | 0.647 (0.620–0.674)* | 0.593 (0.550–0.636)* | 0.615 (0.589–0.641)* | 0.576 (0.537–0.615)* |
*, P<0.001 when compared with nomogram. AJCC, American Joint Committee on Cancer 8th edition; BCLC, Barcelona Clinic Liver Cancer; JIS, Japan Integrated Staging; CNLC, China Liver Cancer staging; CLIP, Cancer of the Liver Italian Program.