Table 2. Subgroup analysis of SII and OS in GC patients.
Variables | No. of studies | HR (95% CI) | P | Heterogeneity | Model used | |
---|---|---|---|---|---|---|
I2, % | Ph | |||||
Age | ||||||
<59 | 5 | 1.72 (1.51, 1.95) | <0.001 | 19.80 | 0.284 | Fixed |
≥59 | 6 | 1.27 (0.96, 1.67) | 0.091 | 77.70 | 0 | Random |
Cut-off | ||||||
<660 | 7 | 1.55 (1.23, 1.95) | <0.001 | 82.80 | 0 | Random |
≥660 | 4 | 1.45 (1.20, 1.75) | <0.001 | 48.90 | 0.118 | Fixed |
Region | ||||||
China | 9 | 1.49 (1.23, 1.80) | <0.001 | 79.50 | 0 | Random |
Turkey | 1 | 2.00 (0.37, 10.86) | 0.424 | – | – | – |
Japan | 1 | 2.19 (1.25, 3.82) | 0.006 | – | – | – |
SII, systemic immune-inflammatory index; OS, overall survival; GC, gastric cancer; HR, hazard ratio; CI, confidence interval.