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. 2021 Apr;12(2):344–354. doi: 10.21037/jgo-20-252

Table 2. Subgroup analysis of SII and OS in GC patients.

Variables No. of studies HR (95% CI) P Heterogeneity Model used
I2, % Ph
Age
   <59 5 1.72 (1.51, 1.95) <0.001 19.80 0.284 Fixed
   ≥59 6 1.27 (0.96, 1.67) 0.091 77.70 0 Random
Cut-off
   <660 7 1.55 (1.23, 1.95) <0.001 82.80 0 Random
   ≥660 4 1.45 (1.20, 1.75) <0.001 48.90 0.118 Fixed
Region
   China 9 1.49 (1.23, 1.80) <0.001 79.50 0 Random
   Turkey 1 2.00 (0.37, 10.86) 0.424
   Japan 1 2.19 (1.25, 3.82) 0.006

SII, systemic immune-inflammatory index; OS, overall survival; GC, gastric cancer; HR, hazard ratio; CI, confidence interval.