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Meta-analysis and migration analysis of the effect of berberine on high-density lipoprotein. Forest plot illustrates the differences in changes in high-density lipoprotein in adults with metabolic disease who did or did not receive berberine in 13 trials (n = 1,133). The mean difference (blue squares), 95% CI (horizontal lines through blue squares), and pooled-effect sizes (green diamonds) were presented using random-effect Hedges models.
