TABLE 5.

Gene set enrichment.

	Up				Down
	Gene ontologies			KEGG_P	Gene ontologies			KEGG_P
	BP	CC	MF		BP	CC	MF
Agomelatine (+) vs. HC	67	10	43	6	667	65	45	37
Agomelatine (−) vs. HC	39	14	16	1	305	41	70	20
Unique for agomelatine	76	6	30	3	639	52	30	45
Melatonin (+) vs. (−)	9	4	2	—	213	28	63	10

BP, biological process; CC, cellular component; MF, molecular function; KEGG_P, KEGG pathway; analysis inclusion threshold, EASE score, a modified Fisher exact p < 0.05.