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. 2021 May;37(3):221–231. doi: 10.6515/ACS.202105_37(3).20210420A

Figure 7.

Figure 7

Breast uptake overlapping the heart in planar and SPECT images. (A) Although the ROI (red circles) was well-delineated in planar view, marked breast physiological uptake was also noted. (B) An axial SPECT slice reveals marked breast uptake (red arrow) and blood pool activity. (C) SPECT/CT fusion images reveal potential causes for false positives of cardiac 99mTc-PYP uptake including blood pool activity, soft tissue uptake such as in the breast, osseous uptake, lung parenchymal lesions, overlying devices, or myocardial infarction. SPECT or SPECT/CT clearly demonstrates uptake in the myocardium or other areas. BKG, background; PYP, pyrophosphate; ROI, region of interest; SPECT/CT, single-photon emission computed tomography/computed tomography; stddev, standard deviation.