Table 1. Recommendations for 99mTc-pyrophosphate scintigraphy acquisition parameters.
| Parameters | |
| Imaging procedure | |
| Specific preparation | None; fasting is not required |
| Scan | Rest scan |
| Dose of 99mTc-PYP | • Recommended: 20 mCi for 3-hour acquisition |
| • Adjust according to different models of instrument | |
| Time interval between injection and acquisition | • Recommended: 3-hour planar and SPECT |
| • Optional: 1-hour planar | |
| Imaging parameters | |
| Field of view | Cardiac or chest |
| Image type | Cardiac or chest planar and SPECT (or SPECT/CT) |
| Position | Supine |
| Energy window | 140 keV, 15-20% |
| Collimators | Low energy, high resolution |
| Matrix | 128 × 128 recommended (64 × 64 minimum required) for SPECT, 256 × 256 for planar |
| Pixel size | 2.3-6.5 mm (may change with different matrix) |
| Planar imaging specific parameters | |
| Number of views | Anterior, lateral, and left anterior oblique (LAO) |
| Detector configuration | 180 degrees |
| Image duration | 750,000 counts |
| Magnification | 1.45-1.5 |
| SPECT imaging specific parameters | |
| Angular range | 360 degrees |
| Detector configuration | 180 degrees |
| ECG gating | Off; non-gated imaging |
| Number of views/detectors | 32-64 |
| Time per stop | 20 seconds |
ECG, electrocardiography; keV, kilo-electronvolts; mCi, millicurie; PYP, pyrophosphate; SPECT, single-photon emission computed tomography; SPECT/CT, SPECT/computed tomography.