Table 3.
Recent patents on SLNs and NLCs.
| Patent/Publication number | Status | Publication/grant date | Assignee | Title | Drugs disclosed | Dosage Form |
|---|---|---|---|---|---|---|
| Solid lipid nanoparticles | ||||||
| CN110585171A | Active | December 12, 2019 | Wuhan Burunnao Medical Technology Co., Ltd. | Temozolomide solid lipid nanoparticle and preparation method thereof | Temozolomide | Oral administration, intravenous injection, pulmonary inhalation, local administration, and the like |
| US20200197360A1 | Active | June 25, 2020 | SRM Institute of Science and Technology | Dispersion of formononetin solid lipid nanoparticles and process for its preparation | Formononetin | Injection |
| WO2020144377A1 | Active | July 16, 2020 | The Queen's University of Belfast | Solvent and water-free lipid-based nanoparticles and their methods of manufacturing | Felodipine, Naproxen, and Ketoconazole | Reconstituted prior to infusion or injection |
| WO2020109989A1 | Active | Jun 04, 2020 | Panjab University Chandigarh | Solid lipid nanoparticles of curcumin | Curcumin | Gel, hydrogel, organogel, syrup, paste, cream, facewash, mouthwash, oral rinse, ointment, liquid ampoule, dispersion, aerosol spray, powder, orthotic aid, liquid oral, FDM facemask, implant, tablet, lozenges, capsules, suppositories, pessaries, patch, and gummies |
| KR20200085529A | Active | Jul 15, 2020 | Chungbuk National University Industry-Academic Cooperation Foundation | Solid lipid nanoparticles for skin permeation and composition for drug delivery comprising the same | Tacrolimus, dexpanterol, and allantoyl | – |
| WO2019206738A1 | Active | Oct 31, 2019 | Chr. Hansen Natural Colors A/S, Københavns Universitet | Pigment-loaded solid lipid nanoparticles | Naturally occurring oil-soluble pigments, such as carotenoids or chlorophylls. Carotenoids include alpha- carotene, beta-carotene, lycopene, lutein, bixin, and norbixin | Used in food products and beverages |
| WO2020028916A1 | Active | February 06, 2020 | University of Mississippi | Amphotericin loaded pegylated lipid nanoparticles and methods of use | Amphotericin | Injection |
| WO2020053609A1 | Active | March 19, 2020 | Lead Biotherapeutics Ltd. | Mucoadhesive dispersion. Nanoparticle system and method for the production of the same | Mometasonefuroate Xylometazoline Loratidine |
Nasal mucoadhesive |
| CN110585121A | Active | December 20, 2019 | Wuhan Burunnao Medical Technology Co., Ltd. | Temozolomide nuclear magnetic resonance visual injectable hydrogel, preparation method and application | Temozolomide | Injectable hydrogel for diagnostic purpose |
| US20200114019A1 | Active | April 16, 2020 | National Yang Ming University | The pH-sensitive lipid nanoparticles for encapsulation of anticancer drugs and microrna and use thereof | Anticancer Drugs: Irinotecan, oxaliplatin, epirubicin, doxorubicin, afatinib, and docetaxel | Injection |
| Nano structure lipid carriers | ||||||
| CN108853056A | Active | Nov 23, 2018 | Tianjin University of Traditional Chinese Medicine | A kind of modification of folate-targeted carries doxorubicin hydrochloride and gambogic acid nano structured lipid carrier preparation and preparation method thereof altogether | Doxorubicin hydrochloride and gambogicacid | – |
| WO2019226186A1 | Active | November 28, 2019 | U.S. Nutraceuticals, Llc D/B/A Valensa International | Composition and method to alleviate joint pain using hyaluronic acid and eggshell membrane components | Hyaluronic acid | Injection |
| US20200010530A1 | Active | January 09, 2020 | Tianxin Wang | Methods and reagents to treat autoimmune diseases and allergy | Peptide-MHC I complex and peptide-MHC II complex | Subcutaneous or intravenous injection |
| CN108685875A | Active | Oct 23, 2018 | China Pharmaceutical University | A kind of natural nano grain-pharmaceutical composition of anti-Alzheimer's disease and its preparation method and application | Cholesteryl ester, phosphatidyl choline, triglycerides, ceramide, and gangliosides | Injection |
| WO2019191780A9 | Active | Jun 18, 2020 | Arcturus Therapeutics, Inc. | Lipid particles for nucleic acid delivery | Antibody or an immunogenic peptide | Subcutaneous injection, intradermal injection, or intramuscular injection |