Table 1. Functional miRNAs regulate macrophage polarization.

miRNAs	Promoted phenotype	Target(s)	Reference(s)
miRNA-155	M1	IL13Rα1, TLR4/IL-1R, C/EBP-β	(147-149)
miRNA-27a	M1	PPAR-γ	(150)
miRNA-27b	M1	PPAR-γ	(151)
miRNA-125a	M1	IRF4	(152)
miRNA-125b	M1	IRF4	(145)
miRNA-21	M1	STAT3	(153)
miRNA-127	M1	Bcl-6, Dusp1, JNK	(154)
miRNA-720	M1	GATA3	(146)
miRNA-223	M1	Pknox1	(155)
miRNA-26a	M1	KLF4	(156)
miRNA-9	M1	PPAR-δ	(157)
miRNA-125b	M1	IRF4	(145)
miRNA-130a	M1	PPAR-γ	(158)
miRNA-130b	M1	PPAR-γ	(159)
miRNA-125a	M2	KLF-13 (in mice)	(160)
miRNA-34a	M2	Notch1	(161)
miRNA-146a	M2	INHBA, TLR4/IRF3, IRAK1, TRAF6	(162-165)
miRNA-146b	M2		(166)
miRNA-223	M2	PBX/Knotted 1 Homeobox 1 (Pknox1), STAT3	(167)
miRNA-210	M2	NF-κB, DR6	(168,169)
miRNA-33	M2	AMPK	(170)
miRNA-222	M2	STAT3	(171)
miRNA-127	M2	DUSP1	(172)
miRNA-132	M2	AchE	(173)
miRNA-124	M2	C/EBP-α, STAT3, TACE	(174,175)
miRNA-145	M2	IL10 gene silencer histone deacetylase 11	(176)
miRNA-93	M2	IRF9	(177)
miRNA-21	M2	SIRPb1	(178)
Let-7c	M2	C/EBP-δ, PAK1	(162,172)
miRNA-181a	M2	KLF6, C/EBP-α	(179)