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. 2021 Apr;10(4):1792–1803. doi: 10.21037/tlcr-21-48

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2021 Translational Lung Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Similarity of primary tumors and metastases on chromosomal level. (A) Repertoire of copy number alterations as defined by WES of primary LUSC (pri), first metastasis (met) and second metastasis (met2) of each patient. Samples represented on the y-axis; chromosomes are represented along the x-axis. Light red: copy number loss; red: homozygous deletion; light blue: copy number gain; dark blue: amplification; (B) ploidy analysis measured using flow cytometry. Samples are represented on the x-axis; ploidy is represented in the y-axis. blue: primary tumor (pri); red: first metastasis (met); green: second metastasis (met2).