Table 2. Clinical characteristics of the cohort.
| Patient | P6 | P9 | P18 | P103 | P109 |
|---|---|---|---|---|---|
| Sex | Male | Male | Male | Male | Male |
| Age at diagnosis (years) | 54 | 61 | 64 | 73 | 68 |
| Smoker at diagnosis | Current | NA | Former | NA | Current |
| Smoking status (pack-years) | 50 | NA | NA | NA | NA |
| pTN* | pT4, pN1 | pT2a, pN0 | pT3, pN0 | pT4, pN1 | pT2a, pN1 |
| Diameter of primary tumor | 5.5 cm | 3.5 cm | 3.2 cm | 7.8 cm | 3.5 cm |
| Radiotherapy | NA | NA | No | No | Yes# |
| Chemotherapy | No | No | No | No | Yes# |
| Time to metastasis (months) | 5 | 8 | 50 | 1 | 0 (Met1) 28 (Met2) |
| Site of metastasis/recurrence | Left kidney | Right kidney | Main bronchial carina | Brain | Interlobular lymph node (pN1) (Met1) thoracic spine (Met2) |
| Ploidy (N) primary tumor | 3.6 | 3.9 | 3.6 | 3.3 | 3.6 |
| Ploidy (N) metastasis | 3.4 | 4 | 3.3 | 3.2 | 2 (Met1) 1.8 (Met2) |
#Palliative radiotherapy and chemotherapy (Cisplatin/Vinorelbine and Cisplatin/Gemcitabine) prior to resection of Met 2; *according to UICC TNM classification (8th Edition). Met1, metastasis 1; Met2, metastasis 2.