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. 2021 Apr;10(4):1169–1200. doi: 10.21037/tp-20-445

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2021 Translational Pediatrics. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Similar non-specific intermediate TE spectral pattern seen at 1.5T (Lac presence, inversion of NAA/tCho ratio) in 6 different pathologies in pediatric patients (voxel placed in areas of abnormal signal on T2-WI, yellow arrows): (A) low grade WHO II astrocytoma; (B) acute disseminated encephalomyelitis (ADEM); (C) herpes encephalitis; (D) progressive multifocal leukoencephalopathy (PML); (E) dysembryoplastic neuroepithelial tumor (DNET); (F) “tumor-like” multiple sclerosis plaque. Acronyms and abbreviations are shown in Appendix 1.