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. 2021 Apr;10(4):1138–1168. doi: 10.21037/tp-20-285

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2021 Translational Pediatrics. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Male, 15 years old, diagnosis of supratentorial ependymoma RELA-fusion. Brain CT shows a median bi-frontal brain lesion with some focus of calcification on the left (A, arrow). Brain MRI (B,C,D,E). T1WI shows a lobulated tumor predominantly hypointense with some hyperintense peripheral areas (B). The T2WI shows a diffuse hyperintensity with some central components, with more hyperintensity related with cystic/necrotic areas (C), susceptibility-weighted imaging demonstrates multiple and confluent hypointense foci inside the tumor compatible with hemorrhage (D), and post-gadolinium contrast T1-weighted shows subtle, sparse foci of enhancement (E). T1WI, T1-weighted image.