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. 2021 Apr 29;5:24705470211011075. doi: 10.1177/24705470211011075

Table 2.

Results of multivariable analyses evaluating the relation between the CNR1 rs1049353 genotype, childhood abuse, and PTSD symptoms.


PTSD symptoms

Re-experiencing

Avoidance

Emotional numbing

Dysphoric arousal

Anxious arousal
F p F p F p F p F p F p
rs1049353 A allele carrier 2.93 0.087 0.05 0.82 0.25 0.62 1.76 0.18 3.04 0.082 26.61 2.9 × 10−7
Childhood abuse 35.51 2.4 × 10−4 6.95 0.008 0.24 0.63 17.77 2.7 × 10−5 18.317 2 × 10−5 2.41 0.12
rs1049353 A allele carrier × Childhood Abuse 11.92 0.001 4.54 0.033 0.01 0.91 8.16 0.004 11 0.001 36.26 2.3 × 10−12

Note. Analyses are adjusted for age, sex, first 10 PCs, combat veteran status, number of lifetime traumas other than childhood abuse, and nature of index trauma (i.e., assaultive vs. non-assaultive).