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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Obstet Gynecol. 2020 Dec;136(6):1086–1094. doi: 10.1097/AOG.0000000000004166

Table 2.

Matched Case–Control Analysis of Stillbirths After Maternal Vaccination During Pregnancy*

Exposure During Pregnancy Vaccination Rate in Stillbirths (n=795) Vaccination Rate in Live Births (n=3,180) Crude OR (95% CI) Adjusted OR (95% CI) P

Any vaccination 411 (51.7) 1,682 (52.9) 0.94 (0.78–1.12) 0.95 (0.78–1.14) .56
Influenza vaccination 343 (43.1) 1,407 (44.3) 0.94 (0.79–1.13) 0.95 (0.79–1.14) .54
Tdap vaccination§ 184 (23.1) 746 (23.5) 0.97 (0.76–1.24) 0.96 (0.76–1.28) .91
Non–routinely recommended vaccinations 9 (1.1) 35 (1.1) 1.03 (0.49–2.17) 0.92 (0.42–2.00) .84

OR, odds ratio; Tdap, tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis.

Data are n (%) unless otherwise specified.

*

Fourteen days after the last menstrual period through 7 days before the index date (stillbirth outcome date or reference date for matched control).

Adjusted for maternal age, smoking during pregnancy, obesity, nulliparity, history of stillbirth, Black non-Hispanic race, and maternal comorbidities and pregnancy complications occurring before vaccination.

Inactivated influenza vaccination with or without Tdap vaccination.

§

Tdap vaccination with or without inactivated influenza vaccination.

Human papillomavirus, meningococcal, pneumococcal, inactivated polio, Japanese encephalitis, rabies, inactivated typhoid, yellow fever, hepatitis A, hepatitis B.