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. 2021 May 10;2021(5):CD013620. doi: 10.1002/14651858.CD013620.pub2

3. Pressure ulcer incidence results reported in studies that compared different types of alternating pressure (active) air surfaces.

Study ID Results Comment
Comparison: alternating pressure (active) air surfaces compared with other types of alternating pressure (active) air surfaces
Demarre 2012 Alternating pressure (active) air surfaces (Hill‐Rom ClinActiv)
  • Proportion of participants developing a new pressure ulcer: 17/298 (5.7%)

  • Time to pressure ulcer development: median time 5.0 days (IQR 3.0 to 8.5)

Alternating pressure (active) air surfaces (Hill‐Rom Alto mattress)
  • Proportion of participants developing a new pressure ulcer: 18/312 (5.8%)

  • Time to pressure ulcer development: median 8.0 days (IQR 3.0 to 8.8)

  • Proportion of participants developing a new pressure ulcer: RR 0.99 (95% CI 0.52 to 1.88).

  • Time to pressure ulcer development: Mann‐Whitney U‐test = 113, P = 0.182 for median time to ulcer incidence; Kaplan Meier plot reported (log‐rank Chi2 = 0.013, df = 1, P = 0.911); HR 0.96 (95% CI 0.50 to 1.87) estimated by the review authors using the methods of Tierney 2007.

Gray 2008 Alternating pressure (active) air surfaces (hybrid air surfaces: Softform Premier Active Mattress)
  • Proportion of participants developing a new pressure ulcer: 4/50 (7.7%)

Alternating pressure (active) air surfaces
  • Proportion of participants developing a new pressure ulcer: 4/50 (7.7%)

  • Proportion of participants developing a new pressure ulcer: RR 1.00 (95% CI 0.26 to 3.78).

Hampton 1997 Alternating pressure (active) air surfaces (hybrid air surfaces: Cairwave Therapy System)
  • Proportion of participants developing a new pressure ulcer: 0/36 (0.0%)

Alternating pressure (active) air surfaces
  • Proportion of participants developing a new pressure ulcer: 0/unspecified number

  • Proportion of participants developing a new pressure ulcer: summary estimate not estimable due to the lack of data.

Nixon 2006 Alternating pressure (active) air surfaces (mattresses)
  • Proportion of participants developing a new pressure ulcer: 101/982 (10.3%)

  • Time to pressure ulcer development: see comments

Alternating pressure (active) air surfaces (overlays)
  • Proportion of participants developing a new pressure ulcer: 106/989 (10.7%)

  • Time to pressure ulcer development: see comments

  • Proportion of participants developing a new pressure ulcer: RR 0.96 (95% CI 0.74 to 1.24).

  • Time to pressure ulcer development: log‐rank test P = 0.759; HR 0.96 (95% CI 0.73 to 1.26) estimated by the review authors using the methods of Tierney 2007.

Rafter 2011 Alternating pressure (active) air surfaces (hybrid air surfaces: Dyna‐Form Mercury Advance)
  • Proportion of participants developing a new pressure ulcer: 0/5 (0.0%)

Alternating pressure (active) air surfaces (hybrid air surfaces: Softform Premier Active)
  • Proportion of participants developing a new pressure ulcer: 2/5 (40.0%)

  • Proportion of participants developing a new pressure ulcer: RR 0.20 (95% CI 0.01 to 3.35).

Taylor 1999 Alternating pressure (active) air surfaces (hybrid air surfaces: Pegasus Trinova)
  • Proportion of participants developing a new pressure ulcer: 0/22 (0.0%)

Alternating pressure (active) air surfaces
  • Proportion of participants developing a new pressure ulcer: 2/22 (9.1%)

  • Proportion of participants developing a new pressure ulcer: RR 0.20 (95% CI 0.01 to 3.94).

Theaker 2005 Alternating pressure (active) air surfaces (hybrid air surfaces: KCI TheraPulse bed with low‐air‐loss feature)
  • Proportion of participants developing a new pressure ulcer: 3/30 (10.0%)

Alternating pressure (active) air surfaces (hybrid air surfaces: Hill‐Rom Duo mattress)
  • Proportion of participants developing a new pressure ulcer: 6/32 (18.8%)

  • Proportion of participants developing a new pressure ulcer: RR 0.53 (95% CI 0.15 to 1.94).

IQR ‐ interquartile range