Skip to main content
. Author manuscript; available in PMC: 2021 May 10.
Published in final edited form as: Mol Cell Neurosci. 2018 Mar 24;89:33–41. doi: 10.1016/j.mcn.2018.03.010

Fig. 3.

Fig. 3.

TrkB.T1 shrinks the population of hippocampal PVi in wt and in mSOD1 mice.

Stereological estimations of hippocampal PVi populations are shown, for each subfield, in graphs for wt (n = 6), mSOD1(n = 5), T1−/− (n = 6), mSOD1/T1−/− (n = 6) mice. For each graph, the ordinate indicates the PVi number. The number of PVi is comparable among groups in DG and CA2. T1 deletion results in an increase of PVi number in CA3. In mSOD1 mice both the PVi populations of CA1 and CA3 are found to be reduced compared to wt animals. Knocking out T1 in mSOD1 mice completely restores PVi population in CA1; in CA3, PVi number increases with respect to mSOD1 mice, albeit below the level of controls. Asterisks denote statistical significant differences (* = p < 0.05; *** = p < 0.01).