TABLE I.
Characteristic | Patients with elevated liver enzymes (n = 9) | Patients without liver enzyme elevation (n = 24) |
---|---|---|
Age (y), mean | 17.1 | 21.5 |
Sex (males), n (%) | 5 (55) | 14 (58) |
Mutation type, n | ||
R1 P-85 | 4 | 2 |
P-110 | 5 | 22 |
Highest ALT* | 65 U/L (62–132) | 22 U/L (15–34) |
ALP (median)* | 175 U/L (99–226) | 95 U/L (68–154) |
Platelets, K/uL (median)* | 248 (164–354) | 192 (145–234) |
Spleen size corrected to height† | 0.94 (n = 7) | 0.81 (n = 16) |
ALP, Alkaline phosphatase; ALT, alanine aminotransferase.
Expressed as median (interquartile range).
Measured in centimeters.