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. 2021 Apr 27;17:17448069211011315. doi: 10.1177/17448069211011315

Figure 2.

Figure 2.

The correlation effect between P2X3 and TRPV1 of CFA rats in vivo. (a) After TRPV1 was activated, the flinching times (2 min intervals) of CFA rats with P2X3 agoinst/P2X3 antagonist. (b) After TRPV1 was activated, the flinching times (10 min intervals) of CFA rats with P2X3 agoinst/P2X3 antagonist. (c) After TRPV1 was activated, the licking time (2 min intervals) of CFA rats with P2X3 agoinst/P2X3 antagonist. (d) After TRPV1 was activated, the licking time (10 min intervals) of CFA rats with P2X3 agoinst/P2X3 antagonist. Compared with CFA+vehicle+capsaicin group, △P<0.05, △△P<0.01, compared with CFA+α,β-meATP+capsaicin group, #P<0.05, ##P<0.01, (CFA+vehicle+capsaicin group: n=4, CFA+α,β-meATP+capsaicin group: n=5, CFA+TNP-ATP+capsaicin group: n=5). (e) After P2X3 was activated, the flinching times (2 min intervals) of CFA rats with TRPV1 agoinst/TRPV1 antagonist. (f) After P2X3 was activated, the flinching times (10 min intervals) of CFA rats with TRPV1 agoinst/TRPV1 antagonist. (g) After P2X3 was activated, the licking time (2 min intervals) of CFA rats with TRPV1 agoinst/TRPV1 antagonist. (h) After P2X3 was activated, the licking time (10 min intervals) of CFA rats with TRPV1 agoinst/TRPV1 antagonist. Compared with CFA+vehicle+α,β-meATP group,△P<0.05, △△P<0.01, compared with CFA+capsazepine+α,β-meATP group, #P<0.05, ##P<0.01, (CFA+vehicle+α,β-meATP group: n=5, CFA+capsaicin+α,β-meATP group: n=5, CFA+ capsazepine +α,β-meATP group: n=6).