Phylogenetic analysis by maximum likelihood method of ST244 lineage (A) and ST695 (B) core genomes. All isolates except for 2 ST244 lineage isolates (outliers from CO) and 4 ST695 lineage isolates (outliers from MN and MD, and a single GA isolate) were recovered in CA. The year the isolate was recovered is indicated by font color (black, 2015; blue, 2016; green, 2017; red, 2018). Homeless individuals are indicated by an asterisk and injection drug abuse is indicated by #. Trees were constructed to scale. Red arrows are situated between genetically indistinguishable isolates. A, included 99 assemblies and 954 positions, while (B) involved 28 assemblies and 647 positions. SNP values are provided for 4 long branches (A) and 2 long branches (B). Abbreviations: CA, California; CO, Colorado; GA, Georgia; MD, Maryland; MN, Minnesota; SNP, single-nucleotide polymorphism.