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. 2021 May 10;40:162. doi: 10.1186/s13046-021-01936-4

Fig. 1.

Fig. 1

Timeless is upregulated in CRC tissues and associated with poor prognosis. (a) Representative images from the immunohistochemical analyses of Timeless protein expression in normal colorectal tissues and colorectal cancer tissues. (b) Statistical analyses of the H-score of Timeless staining in CRC and corresponding normal tissues. (c) Representative images from immunohistochemical analyses of Timeless protein expression in CRC tissues at different clinical stages. (d) Statistical analyses of the H-score of Timeless staining in CRC tissues at different clinical stages. (e) Kaplan–Meier survival curves showing an association between Timeless and the overall survival in patients with CRC