Table 1.
Case counts and incidence rates (per 1,000,000 population) for pediatric cancers by ICCC-3 site classification among Alaska Native children, diagnosed 1969-2016, stratified by time-period.a,b
| 1969-2016 | 1969-1996 | 1997-2016 | ||||
|---|---|---|---|---|---|---|
| All ages (00-19 years) | All ages (00-19 years) | All ages (00-19 years) | ||||
| Count | IR (95% CI) | Count | IR (95% CI) | Count | IR (95% CI) | |
| All ICCC Cancers | 320 | 167.5 (149.6, 186.9) | 134 | 139.8 (117.0, 165.7) | 186 | 197.5 (170.1, 228.1) |
| I Leukemias, myeloproliferative & myelodysplastic diseases | 97 | 49.6 (40.2, 60.5) | 36 | 36.6 (25.6, 50.8) | 61 | 64.1 (49.0, 82.3) |
| Acute lymphocytic leukemia | 60 | 30.3 (23.1, 39.0) | 24 | 24.5 (15.6, 36.5) | 36 | 37.4 (26.2, 51.8) |
| Acute myeloid leukemia | 20 | 10.5 (6.4, 16.2) | 14 | 14.9 (8.2, 25.0) | ||
| II Lymphomas and reticuloendothelial neoplasms | 44 | 23.2 (16.9, 31.2) | 14 | 14.8 (8.0, 24.8) | 30 | 32.3 (21.7, 45.9) |
| Hodgkin lymphomas | ||||||
| Non-Hodgkin lymphomas (except Burkitt lymphoma) | 17 | 9.2 (5.4, 14.8) | 13 | 14.1 (7.5, 24.1) | ||
| III CNS and misc intracranial and intraspinal neoplasms | 47 | 24.8 (18.2, 33.0) | 18 | 18.7 (11.0, 29.5) | 29 | 31.2 (20.9, 44.8) |
| IV Neuroblastoma and other peripheral nervous cell tumors | ||||||
| V Retinoblastoma | 10 | 4.9 (2.3, 9.0) | ||||
| VI Renal tumors | 17 | 8.4 (4.9 , 13.6) | ||||
| VII Hepatic tumors | 24 | 12.8 (8.2, 19.0) | 18 | 19.7 (11.7, 31.1) | ||
| VIII Malignant bone tumors | 12 | 6.4 (3.3, 11.2) | ||||
| IX Soft tissue and other extraosseous sarcomas | 23 | 12.3 (7.8, 18.4) | 15 | 16.2 (9.0, 26.6) | ||
| X Germ cell & trophoblastic tumors & neoplasms of gonads | 10 | 5.4 (2.6, 9.9) | ||||
| XI Other malignant epithelial neoplasms and melanomas | 27 | 15.4 (10.1, 22.3) | 18 | 19.8 (11.8, 31.3) | ||
| XII Other and unspecified malignant neoplasms | ||||||
a
Data not given where case count <10.
b
IR: Incidence rate; CI: Confidence interval.