Table 2.
Case counts and twenty-five year average annual incidence rates (per 1,000,000 population) for pediatric cancers by ICCC-3 site classification among Alaska Native and U.S White children, diagnosed 1992-2016.a
| Alaska Native | U.S. White | |||
|---|---|---|---|---|
| All ages (00-19 years) | All ages (00-19 years) | |||
| Count | IR (95% CI) | Count | IR (95% CI) | |
| All ICCC-3 Cancers | 206 | 178.1 (154.5, 204.2) | 36628 | 180.5 (178.6, 182.3) |
| I Leukemias, myeloproliferative & myelodysplastic diseases | 69 | 58.3 (45.4, 73.9) | 10008 | 48.9 (48, 49.9) |
| Acute lymphocytic leukemia | 47 | 39.2 (28.8, 52.2) | 7836 | 38.3 (37.4, 39.1) |
| Acute myeloid leukemias | 16 | 13.9 (7.9, 22.6) | 1648 | 8.1 (7.7, 8.5) |
| II Lymphomas and reticuloendothelial neoplasms | 24 | 21 (13.5, 31.3) | 5113 | 25.6 (24.9, 26.3) |
| Hodgkin lymphomas | 2605 | 13.1 (12.6, 13.6) | ||
| Non-Hodgkin lymphomas (except Burkitt lymphoma) | 10 | 9 (4.3, 16.5) | 1774 | 8.9 (8.4, 9.3) |
| III CNS and misc intracranial and intraspinal neoplasms | 30 | 26.2 (17.7, 37.4) | 6260 | 30.8 (30.1, 31.6) |
| IV Neuroblastoma and other peripheral nervous cell tumors | 1734 | 8.2 (7.9, 8.6) | ||
| V Retinoblastoma | 692 | 3.3 (3, 3.5) | ||
| VI Renal tumors | 11 | 9.2 (4.6, 16.5) | 1355 | 6.5 (6.2, 6.9) |
| VII Hepatic tumors | 12 | 10.3 (5.3, 18) | 498 | 2.4 (2.2, 2.6) |
| VIII Malignant bone tumors | 1870 | 9.4 (9, 9.8) | ||
| IX Soft tissue and other extraosseous sarcomas | 17 | 15.1 (8.8, 24.2) | 2414 | 11.9 (11.5, 12.4) |
| X Germ cell & trophoblastic tumors & neoplasms of gonads | 2671 | 13.3 (12.8, 13.8) | ||
| XI Other malignant epithelial neoplasms and melanomas | 19 | 17.7 (10.6, 27.5) | 3900 | 19.6 (19, 20.2) |
| XII Other and unspecified malignant neoplasms | 113 | 0.6 (0.5, 0.7) | ||
a
Data not given where case count <10.
b
ICCC-3: International Classification of Childhood Cancers, 3rd edition; IR: Incidence rate; CI: Confidence interval.