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. Author manuscript; available in PMC: 2021 May 10.
Published in final edited form as: J Head Trauma Rehabil. 2020 Sep-Oct;35(5):317–323. doi: 10.1097/HTR.0000000000000619

TABLE 4.

Median baseline marker levels in patients who received TXA early (<45 minutes) versus late (≥45 minutes) relative to time of injury

Early (<45 min) Late (≥45 min)
Marker n Median [IQR] n Median [IQR] P
Syndecan-1 77 234.4 [200.1–293.3] 79 270.1 [201.1–358.0] .09
ICAM-1 76 40 492.4 [30 446.2–56 903.7] 79 46 502.6 [32 971.5–63 558.4] .16
VCAM-1 77 63 801.8 [49 866.8–86 826.1] 79 63 678.0 [49 133.7–87 963.5] .70
Thrombomodulin 77 583.5 [478.4–707.8] 79 605.7 [520.7–723.3] .42
Thrombospondin-2 77 1 954.9 [1 363.0–2 820.8] 79 1 991.4 [1 516.9–2 596.0] .46
Angiopoietin-1 77 371.5 [266.7–690.9] 78 532.6 [346.2–768.6] .08
Angiopoietin-2 77 142.6 [94.0–171.8] 79 155.4 [111.3–211.3] .05

Abbreviations: ICAM-1, intercellular adhesion molecule 1; IQR, interquartile range; TXA, tranexamic acid; VCAM-1, vascular cell adhesion protein 1.