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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Bone. 2021 Apr 7;148:115946. doi: 10.1016/j.bone.2021.115946

Table 3.

Prevalence and odds ratio (OR) of fracture measures for adults with and without LAL-D.

With LAL-D (n=3,076) Without LAL-D (n=13,683,481) p-value Model 1 Reference: without LAL-D Model 2 Reference: without LAL-D
Fracture  % (n) % (n) OR (95% CI) OR (95% CI)
Any fracture 5.8 (179) 3.6 (494,911) <0.001 1.23 (1.05, 1.43) 1.21 (1.03,1.41)
Site-specific fracture
 Cervical/thoracic vertebra 0.8 (24) 0.4 (60,612) 0.005 1.23 (0.82, 1.84) *
 Lumbar spine/pelvis 1.0 (31) 0.7 (94,963) 0.036 1.00 (0.70, 1.42) 0.97 (0.68, 1.38)
 Shoulder/arm/forearm 1.7 (51) 1.2 (160,553) 0.013 1.10 (0.84, 1.46) 1.09 (0.83, 1.44)
 Femur/lower leg/ankle 2.9 (89) 1.4 (196,551) <0.001 1.51 (1.22, 1.87) 1.49 (1.21, 1.85)
Site unspecified
 Stress fracture 0.5 (14) 0.3 (41,163) 0.118 * *
 Pathological/non-traumatic fracture 0.9 (28) 0.5 (67,848) 0.001 1.26 (0.87, 1.83) 1.19 (0.81, 1.75)

CI, confidence interval.

Model 1 adjusted for age, sex, race, and region of residence.

Model 2 adjusted for age, sex, race, region of residence, and osteoporosis.

*

Sample size insufficient for further adjustment.