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. Author manuscript; available in PMC: 2021 Oct 12.
Published in final edited form as: ACS Biomater Sci Eng. 2020 Sep 10;6(10):5941–5958. doi: 10.1021/acsbiomaterials.0c01075

Figure 6. Anti-CD3 treatment selectively depleted naïve CD4+ T cells.

Figure 6.

At ~13 weeks of age, three days after completing a five-day aCD3 treatment regimen, a selection of mice from each group was bled to assess circulating blood lymphocyte phenotype (n = 9–10/group). (A) Representative flow analysis is shown. (B) The ratio of naïve (CD62L+CD44−) to memory (CD62L−CD44+) CD4+ T cells in blood. *P-values ≤ 0.05 were determined by one-way ANOVA with Tukey’s multiple comparison test. Data is represented by mean ± SEM. Full gating scheme – see Supplemental Figure 10.