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. Author manuscript; available in PMC: 2021 Oct 12.
Published in final edited form as: ACS Biomater Sci Eng. 2020 Sep 10;6(10):5941–5958. doi: 10.1021/acsbiomaterials.0c01075

Table 1. Characterization of updated dMP (udMP) formulation.

The loading efficiencies of encapsulated agents and mass delivered per 2.5 mg PLGA injection was calculated (n = 3). Data is represented by mean ± SD.

Encapsulated Agent Mass Loaded/PLGA (μg/ 100 mg) Encapsulation Efficiency ± SD (%) Mass Delivered per Injection ± SD (ng)
Denatured Insulin 2580 65 ± 7 41,500 ± 4,400
Vitamin D3 10 66 ± 3 165 ± 10
TGF-β1 15 50 ± 5 190 ± 20
GM-CSF 64 57 ± 6 900 ± 100