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. 2012 Jul 26;14(10):657–664. doi: 10.1111/j.1751-7176.2012.00686.x

Table IV.

 Three Main Mechanisms of Hypertension and the Antihypertensive Drugs That Target Them

Mechanism Effective Drug Classes
Volume Diuretics, calcium channel blockers
Renin‐angiotensin system Angiotensin‐converting enzyme inhibitors, angiotensin receptor blockers, direct renin inhibitors, β‐blockers
Sympathetic nervous system β‐Blockers, α‐blockers, central α‐agonists