Table I.

 Mean Changes From Baseline in SBP and DBP With TadalaChanges From Baseline Between Sildenafil and Placebo and Between Sildenafil afil or Placebo in Patients Taking ≥1 Antihypertensive Drug

One Drug	Tadalafil (n=140)	Placebo (n=59)
Baseline SBP, mm Hg	143	142
Mean change, mm Hg	−5.7	−3.4
Baseline DBP, mm Hg	83	85
Mean change, mm Hg	−2.2	−2.1
≥2 Drugs	Tadalafil (n=140)	Placebo (n=137)
Baseline SBP, mm Hg	126	44
Mean change, mm Hg	−2.6	+0.9
Baseline DBP, mm Hg	83	82
Mean change, mm Hg	−2.7	−2.2

Abbreviations: DBP, diastolic blood pressure; SBP, systolic blood pressure. Adapted and modified from Kloner et al. ³¹