Table I.
Baseline Characteristics
| Covariate | Overall | C+L/H+L Group | H+L/C+L Group |
|---|---|---|---|
| (N=23) | (n=9) | (n=14) | |
| Age, y | 54.0 (7.5) | 52.7 (9.21) | 54.9 (6.39) |
| Sex (male) | 10 (43.5%) | 3 (33.3%) | 7 (50.0%) |
| Race (white) | 23 (100.0%) | 9 (100.0%) | 14 (100.0%) |
| BMI, kg/m2 | 38.2 (7.53) | 38.5 (6.89) | 38.0 (8.17) |
| SBP, mm Hg | 136 (12.1) | 135 (8.7) | 137 (14.0) |
| DBP, mm Hg | 83.9 (10.3) | 84.9 (7.1) | 83.3 (12.2) |
| Heart rate, beats per min | 71.3 (9.12) | 74.3 (10.8) | 69.3 (7.64) |
| Total cholesterol, mg/dL | 183 (37.5) | 199 (34.8) | 172 (36.6) |
| LDL cholesterol, mg/dL | 104 (33.1) | 116 (35.2) | 96.4 (30.4) |
| HDL cholesterol, mg/dL | 51.0 (12.1) | 58.2 (10.5) | 46.4 (11.0) |
| Triglycerides, mg/dL | 138 (41.5) | 123 (21.9) | 148 (48.5) |
| Glucose, mg/dL | 97.5 (11.2) | 92.4 (8.63) | 101 (11.7) |
| Insulin, mU/La | 8.39 (4.54) | 7.0 (6.06) | 9.27 (3.29) |
| HOMA‐IRa | 2.05 (1.22) | 1.69 (1.64) | 2.28 (0.88) |
| RHIb | 2.12 (0.59) | 2.11 (0.53) | 2.13 (0.64) |
| EIHI | 3.09 (3.1) | 4.17 (4.0) | 2.39 (2.26) |
| oxLDL, U/L | 48.3 (11.7) | 52.3 (7.59) | 45.7 (13.4) |
| 8‐Isoprostane, pg/mL | 7.9 (11.5) | 6.81 (7.67) | 8.61 (13.6) |
| ADMA, μmol/L | 0.46 (0.06) | 0.45 (0.06) | 0.46 (0.05) |
Abbreviations: ADMA, asymmetric dimethylarginine; BMI, body mass index; DBP, diastolic blood pressure; EIHI, endothelium‐independent hyperemic index; HDL, high‐density lipoprotein; HOMA‐IR, homeostasis model assessment of insulin resistance; LDL, low‐density lipoprotein; oxLDL, oxidized low‐density lipoprotein; RHI, reactive hyperemic index; SBP, systolic blood pressure. Data are shown as mean (standard deviation) and No. (%) where indicated. aFive patients missing data. bOne patient missing the value at the end of washout only.