Table IV.
Overall (N=27) | Initial SBP ≥160 mm Hg (n=10) | |||
---|---|---|---|---|
Drug | Preinter‐vention | Postinter‐vention | Preinter‐vention | Postinter‐vention |
Thiazide or loop diuretic | 26 | 27 | 10 | 10 |
K+‐sparing diuretic | 2 | 18 | 1 | 5 |
CCB | 11 | 7 | 7 | 6 |
ACE inhibitor, ARB, or DRI | 24 | 23 | 8 | 9 |
Vasodilator | 5 | 1 | 2 | 1 |
Central α‐agonist | 7 | 6 | 3 | 3 |
β‐Blocker | 21 | 19 | 8 | 8 |
Metabolizeda | 16 | 5 | 5 | 3 |
Nonmetabolizedb | 6 | 14 | 3 | 5 |
α‐Blocker | 7 | 16 | 1 | 5 |
Drugs, No. | 4.1±1.3 | 4.4±1.3 | 4.6±2.0 | 5.1±1.6 |
Abbreviations: ACE, angiotensin‐converting enzyme; ARB, angiotensin receptor blocker; CCB, calcium channel blocker; DRI, direct renin inhibitor; SBP, systolic blood pressure. aCarvedilol, labetalol, metoprolol. bAtenolol, betaxolol, bisoprolol, nebivolol.