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Time course of production of (A) biomass, (B) cytotoxic secondary metabolites in PDB culture of Aspergillus sp., and (C) effect of the different solvent extract on cytotoxicity. The fungus was grown for the different time intervals in PDB. The mycelium was harvested, dried, and weighed as described in Materials and Methods. cytotoxic effect of the extracts on HeLa cells was determined by the MTT assay. Means sharing different letters differ significantly from each other at p ≤ 0.05.
