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. 2021 Apr 26;12:658677. doi: 10.3389/fphar.2021.658677

FIGURE 1.

FIGURE 1

Protective effect of DEX in CLP-induced liver injury. (A) Effect of DEX on the survival rate of septic mice in different groups. C57 mice were subjected to CLP surgery, and survival (n = 31 for each CLP group, and n = 8 for control group) was monitored for 120 h. (B) Image of entire liver taken from mice 24 h after CLP surgery in the CON, CLP, and CLP + DEX groups. (C) The role of DEX in pathological liver injury in septic mice in CON, CLP, and CLP + DEX group at 6, 12, and 24 h (Hematoxylin-and-Eosin stain; magnification: × 400). *p < 0.05. CON: control; CLP: cecal ligation and puncture; DEX: dexmedetomidine.