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Effect of DEX on AMPK/SIRT1 pathway activation in vivo. (A) The protein expression of AMPK, p-AMPK, and SIRT1 in liver tissues as determined using western blotting. (B) The SIRT1 translocation of each group was analyzed using immunohistochemistry (magnification 400 ×). (C) Densitometric analysis of the related bands from (A). (D) Analysis of the optical densities for SIRT1 from (B). Error bars on the bar graphs represent the mean ± SD. *p < 0.05, **p < 0.01.
