Table 2.
Demographics of replication cohorts
| COPDGene—Emory | SPIROMICS—Metabolon | SPIROMICS—UC | p | |
|---|---|---|---|---|
| No. of participants | 271 | 445 | 76 | NA |
| Agea | 67.3 (8.4) | 65.3 (8) | 61.6 (8) | <0.001 |
| Male sex (%) | 127 (46.9) | 244 (54.8) | 40 (52.6) | 0.1164 |
| BMI (%) | 28.7 (5.8) | 28.1 (4.9) | 28.3 (4.8) | 0.3675 |
| Current smoker (%) | 57 (21.0) | 116 (26.4) | 19 (25.7) | 0.2665 |
| Smoking pack-yearsa | 43.9 (23.3) | 47.8 (31.6) | 43.2 (24) | 0.1362 |
| FEV1pp_utaha | 77.1 (25.3) | 79.4 (23.5) | 89.3 (20.8) | 0.0004 |
| FEV1/FVCa | 0.7 (0.1) | 0.6 (0.1) | 0.7 (0.1) | 0.0015 |
| Percent emphysemaa | 6.9 (9.7) | 6.1 (8.2) | 4 (4.8) | 0.038 |
Chi-square tests were used to test for differences between groups in binary variables. One-way ANOVA tests were performed to test for differences between groups in continuous variables.
a
Mean and standard deviation provided unless otherwise noted.