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. 2021 Apr 16;13(8):11491–11506. doi: 10.18632/aging.202841

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Copyright: © 2021 Hu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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FTL and FTH1 levels were positively correlated with some of 47 distinct immune-related markers in 32 solid tumors. (A) FTL level was positively related to some immune-related markers, of which the most 2 were TIM-3 (26/32, 81.3%) and LAIR1 (26/32, 81.3%). Besides, FTL level was positively related to PD-1 in 14/32 cancers (43.8%), PD-L1 in 10/32 (31.3%), CTLA4 in 13/32 (40.6%), and LAG3 in 13/32 (40.6%). (B) FTH1 level was positively related to some immune-related markers, of which the most 2 were TIM-3 (20/32, 62.5%) and LAIR1 (19/32, 59.4%). Besides, FTH1 level was positively related to PD-1 in 4/32 (12.5%) cancers, PD-L1 in 9/32 (28.1%), CTLA4 in 7/32 (21.9%), and LAG3 in 2/32 (6.3%).