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. 2021 Apr 22;13(8):12007–12015. doi: 10.18632/aging.202905

Figure 3.

Figure 3

Overexpression of LINC00514 induced cell growth and EMT progression in GC cells. (A) The level of LINC00514 was overexpressed in SGC-7901 and HGC-27 cells after transfection with pcDNA-LINC00514. (B) Elevated expression of LINC00514 increased Ki-67 expression in both SGC-7901 and HGC-27 cells. (C) The expression of CDK2 in SGC-7901 and HGC-27 cells was measured by qRT-PCR. (D) Overexpression of LINC00514 induced cell growth in both SGC-7901 and HGC-27 cells. (E) Ectopic expression of LINC00514 inhibited E-cadherin expression and increased vimentin and N-cadherin expression. *p<0.05, **p<0.01 and ***p<0.001.