. 2021 Mar 19;13(8):11061–11082. doi: 10.18632/aging.202721

Table 1. Levels of TC, TG, LDLC, HDLC and Ca²⁺ were increased in AS mice and could be reduced by NOX4 knockout (mmol/L).

Group	TC	TG	LDLC	HDLC	Ca²⁺
Normal	4.41 ± 0.34	1.21 ± 0.39	1.13 ± 0.29	2.26 ± 0.24	2.39 ± 0.38
AS	16.87 ± 1.39^*	4.22 ± 0.57^*	5.82 ± 0.99^*	2.61 ± 0.31	3.57 ± 0.67^*
N-NOX4^-/-	5.64±0.31	1.53 ± 0.31	1.21 ± 0.11	2.21 ± 0.20	2.41 ± 0.22
AS-NOX4^-/-	7.62 ± 0.27	2.22 ± 0.57	2.71 ± 0.11	2.26 ± 0.21	2.71 ± 0.25

Note: NOX4, NADPH oxidase 4; AS, atherosclerosis; TC, total cholesterol; TG, triglyceride; LDLC, low density lipoprotein cholesterol; HDLC, high density lipoprotein cholesterol; the data were analyzed by one-way ANOVA with Tukey's test; n = 10; * p < 0.05 vs. the normal group.

Table 1. Levels of TC, TG, LDLC, HDLC and Ca2+ were increased in AS mice and could be reduced by NOX4 knockout (mmol/L).

Table 1. Levels of TC, TG, LDLC, HDLC and Ca²⁺ were increased in AS mice and could be reduced by NOX4 knockout (mmol/L).