Table 2. The aortic plaque formation in AS mice could be prevented by NOX4 knockout.

Group	Plaque area (× 103 um2)	Plaque area/Vascular area
Normal	201.54 ± 15.27	0.46 ± 0.05
AS	542.43 ± 17.69*	0.72 ± 0.08*
N-NOX4-/-	191.76 ± 12.85	0.53 ± 0.04
AS-NOX4-/-	208.46 ± 20.33	0.49 ± 0.07

Note: The data were analyzed by one-way ANOVA with Tukey's test; n = 10; ^* p < 0.05 vs. the normal group; AS, atherosclerosis; NOX4, NADPH oxidase 4.